Mine has let me down twice, first time was about 6 months after purchase when it wouldn't start. Tried again a day later and it worked fine. After checking the forums I concluded it was probably a dying crank sensor (no fault code), changed it and the problem has never been back.
Second time was about a month ago when it started making an awful popping sound, still running but slightly down on power. Had to call recovery--first time ever--who concluded one of the plugs had blown out of the head :O. When I got round to investigating it turned out the thread had stripped so it was a bit of a pain to sort but is now running sweet again, and I got a few other maintenance jobs done while I was in there anyway.
So all-in mine has been pretty good, a few relatively minor failures that have put it off the road for a short time but considering the mileage I can't really complain too much. Just make sure it's been well maintained, especially with regard to cam belt and tensioner changes.
If it's a manual gearbox version the box will probably outlive the car. Clutch can wear out depending on how it's driven but they're not expensive or a big job to change--mine was done recently at nearly 170K and it cost me less than £200 all-in inc labour and genuine VX pressure plate, clutch plate and release bearing.