There is actually a very serious side to this matter, and one I was taught many years ago when I was an RAF instructor having to teach mixed-sex flight deck crews about things like "Crew co-operation", "Flight deck gradients", and other aspects of working together in a small metal box at great heights, under great pressure for up to 21 hours at a time. Under those conditions how, and why, people react to even the smallest thing, is very important.
Many folk don't know that we are ALL, every single one of us, born "female", and for the first 6 weeks or so we develop as females. If, after that time, we have the "correct" chromosone mix, ( XX female; XY male), then, in theory, the "male" body will produce a hormone that starts the embryo to change from female to male.
All sounds very simple, and 90% of the time it works as advertised. However (theres always one of them) when things go wrong there are problems.
Keeping it simple, as it is quite complex at times, if the hormone level is on time and correct then the female embryo turns into a "normal" male. The earlier the hormone kicks in the more "macho" the male becomes, and if it kicks in early, and at a high level, you end up with the stereotypical "ultra male".
When the hormone kicks in late is usually the problem, as the later it is, or the lower the level is, the more "female" the foetus is, and a "late and low" level leads to a very effeminate male.
It has recently been proved that the majority of males going for "sex changes" are in this category, they think and feel they are female because their bodies (and brains) developed as female for much longer than perhaps they should have.
BTW, if a "true" female (XX) gets a kick of the same hormone when they shouldn't, it causes "maleness" problems ... stereotypically the "butch" female. In the worst cases it leads to actualy having both sets of sex organs, or the problems that Caster Semenya is having.
Finally, (and you'll be pleased I've finished

) the question arises, "Why is this happening so much now, it didn't happen when I was a kid" .. well actually it did, but it was swept under the carpet and kept quiet, but it was certainly less publicised.... but is it actually more "common" now, is it it just "more publicity" ??
There is a school of thought, presently unproven, that the amount of hormones being used both in agriculture (growth hormones) and in everyday life (mainly the hormones in birth control pills, women pass these when passing water, so they enter the water cycle) are affecting us by contaminating the water we need to survive, The only proven studies show that fish are affected .... whose to say that we humans are not
https://www.telegraph.co.uk/news/2017/07/02/fish-becoming-transgender-contraceptive-pill-chemicals-flushed/So the behaviour of some folks is actually not under their control, why should we treat them badly when it is their own bodies makeup that is causing them, and society (who can't accept the truth) all the problems ??