If it was a possibility, I would take the train. There is no finer way to travel, imho ofc. Once out of UK trains become an efficient pleasure. 
We did look at the train but, TBH, it's not a lot cheaper than the other options and it's 28+ hours non stop travelling... Plus we need a car at the other end to get to the villa and shopping etc.
Just re-done the costings as I'd well and truly over-estimated things so done them more accurately now. Still left plenty of margin for error on Driving and less on flying though

Looks like to Drive, return trip including hotels, meals, ferry, tolls etc is about £100 more than to Fly, Park, Hire a plastic rental heap, and stop at the airport the night before each flight (because they're at 06:30

)
Hmm.... I think I sense a road trip coming on. Don't fancy being at the airport for 04:30 each day for a crappy Ryanair flight anyway. Add to that the fact that at 6'4" I struggle to fit behind any seats on a Ryanair plane (have to sit bolt upright and still not enough room for my legs without ramming them against the upright seat back in front

)
At least if we drive we're on our own schedule and can do a bit of shopping to bring back without worrying about weight limits

My thinking is to get an afternoon/evening Ferry Dover-Dunkirk, then stay in a hotel near the port (after a supermarket stop for supplies for the next 2 days). Then leave off fairly early (about 7am) and drive via Belgium, Luxembourg and Switzerland (thanks for putting me right on the best route Jim

) to Lake Como, stop for the night and then set off, again fairly early, the following day for the 550 miles or so to the Villa.
On the return, probably a mirror of the journey down.
Suppose the other option would be to buy ourselves a cheap little tent and camp for the night by the lakes in each direction
