Theory is if it works as advertised we won't notice any change at all, as the pressure won't vary at all.
Only if noticing a variation or a change in pressure (thats not a leak) would it be needed!
There is also the theory that Nitrogen is a gas with bigger particles or molecules. So there for normal air loss won't happen, but as said, ime clean the wheel rim to give a good seal and that's negligible anyway(within the confines of regular tyre pressure checks anyway) Something almost always over looked at fast fit places until the owner decides they have a slow puncture.
In the past I have considered fitting tyre pressure sensors in an effort to fully understand operating temps, cold temps, temp changes and obviously be warned of a puncture etc. But they ain't cheap, and how far do you go with it all. Plus real time data and it's usefulness is never apparent until actually fitted and working. By then, if it's crap, it's too late.
I have a compressor in the garage anyway, so that's far more convenient than nipping up the petrol station.