I have until recently been using Chrome for a long time (prior to that Firefox).
2/3 weeks ago started to get the Flash problem and despite the fix in the target line it doesn't work! Seems much, much slower than it ever was.
You can see where IE8 got everything from!
I've moved to Safari which I'm liking so far
IE8 as fall back
Thats the thing - most browsers are fast and stable until all the plugins start destroying them. IE seems particularly prone, possibly due to having more plugins (check what you have installed, its shocking).
Pre-Vista, I used to rebuild my home PCs every 2 to 3 months to keep performance up (XP bogs down with time), so didn't mind IE6.
Post Vista, I tend to only rebuild come Service Pack time to maintain performance, so over that 12-18 month period, all sorts of different browsers find their way on my machines, though I tend to use IE8/9 as my daily choice due to being the most compatible, reverting to others when the mood takes me.